It takes considerable practice to master the art of “running a column”. This video will get you started, with tips on picking appropriate conditions, packing and running a column, monitoring separation, and even making a micro-column from a pipet.
View the complete course: http://ocw.mit.edu/5-301IAP04
License: Creative Commons BY-NC-SA
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Two Americans and a U.S.-based Japanese scientist won the Nobel Prize in chemistry on Wednesday for research on a glowing jellyfish protein that revolutionized the ability to study disease and normal development in living organisms. (Oct.
An organic chemistry-themed music video parodying Robert Palmer’s 1985 “Addicted to Love.”
Shot on Canon XL-1s (MiniDV) w/ Canon XL 5.5-88mm IS II 16X lens. Edited on Sony Vegas HD 6.
***LYRICS***
Your lights are on, but you’re not home
You’re in the lab, working alone.
Your synthesis is nearly done
Just add a chain to that carbon.
You can’t wait to alkylate
But first you must deprotonate
You add a mole of LDA
To overcome that pKa
Whoa, you like to think it will react with the stuff, oh yeah
It’s closer to? the truth to say you can’t add enough
You know you’re gonna have to face it, it’s resistant to base.
You check pH, it’s past fourteen
Your stirring bar is dissolving
The TLC shows no products
Another mole and then reflux!
With LDA, it won’t react
Butyllithium just might abstract
That hydrogen that won’t obey
Le Chatelier’s communiqué
Whoa, you like to think it will react with the stuff, oh yeah
It’s closer to the truth to say you? can’t add enough
You know you’re gonna have to face it, it’s resistant to base.
REFRAIN
Might as well face it, it’s resistant to base. (x5)
Your potassium t-butoxide
And ammonium hydroxide
Your KOH and hydrazine
Push the pH beyond eighteen
Chemistry 3B: Chemical Structure and Reactivity. Spring 2006. Professor Peter Vollhardt.
Chemistry 3B represents the second semester of … all » the standard organic chemistry series at UC Berkeley. It covers conjugation, aromatic chemistry, carbonyl compounds, carbohydrates, amines, carboxylic acids, amino acids, peptides, proteins, and nucleic acid chemistry. Ultraviolet spectroscopy and mass spectrometry will be introduced. Organic chemistry is a specific discipline within the subject of chemistry. It is the scientific study of the structure, properties, composition, reactions, and preparation of chemical compounds of carbon and hydrogen, which may contain any number of other elements, such as…